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pentobarbital will lessen the extent or impact of gefitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lessen the level or influence of conivaptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.CYP3A4 inducers may increase the metabolism of clopidogrel to its Energetic metabolite. Watc